<p class="p1">Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines</p>

Mar 20, 2025

Publications

Endogenous viral elements constitute a complementary source of antigens for personalized cancer vaccines

Publication: npj Vaccines
By: Christian Garde, Michail A. Pavlidis, Pablo Garces, Emma J. Lange, Sri H. Ramarathinam, Mateo Sokač, Kirti Pandey, Pouya Faridi, Johanne Ahrenfeldt, Shanzou Chung, Stine Friis, Daniela Kleine-Kohlbrecher, Nicolai J. Birkbak, Jens V. Kringelum, Birgitte Rønø, Anthony W. Purcell & Thomas Trolle

Mapping the immunopeptidome of seven SARS-CoV-2 antigens across common HLA haplotypes

Sep 2, 2024

Publications

Mapping the immunopeptidome of seven SARS-CoV-2 antigens across common HLA haplotypes

Publication: Nature Communications
Authors: Asolina Braun, Louise C. Rowntree, Ziyi Huang, Kirti Pandey, Nikolas Thuesen, Chen Li, Jan Petersen, Dene R. Littler, Shabana Raji, Thi H. O. Nguyen, Emma Jappe Lange, Gry Persson, Michael Schantz Klausen, Jens Kringelum, Shanzou Chung, Nathan P. Croft, Pouya Faridi, Rochelle Ayala, Jamie Rossjohn, Patricia T. Illing, Katherine E. Scull, Sri Ramarathinam, Nicole A. Mifsud, Katherine Kedzierska, Anders Bundgård Sørensen & Anthony W. Purcell

Benchmarking NGS-Based HLA Typing Algorithms

Aug 21, 2024

Publications

Benchmarking NGS-Based HLA Typing Algorithms

Publication: Springer Protocols
Authors: Nikolas Thuesen and Michael Schantz Klausen

Dose escalation study of a personalized peptide-based neoantigen vaccine (EVX01) in patients with metastatic melanoma

May 29, 2024

Publications

Dose escalation study of a personalized peptide-based neoantigen vaccine (EVX01) in patients with metastatic melanoma

Publication: Journal for ImmunoTherapy of Cancer
Authors: Sofie Kirial Mørk, Signe Koggersbøl Skadborg, Benedetta Albieri,  Arianna Draghi , Kalijn Bol , Mohammad Kadivar, Marie Christine Wulff Westergaard, Joachim Stoltenborg Granhøj, Annie Borch, Nadia Viborg Petersen, Nikolas Thuesen, Ida Svahn Rasmussen, Lars Vibe Andreasen, Rebecca Bach Dohn, Christina Westmose Yde, Nis Noergaard, Torben Lorentzen, Anders Bundgaard Soerensen, Daniela Kleine-Kohlbrecher, Anders Jespersen, Dennis Christensen, Jens Kringelum, Marco Donia, Sine Reker Hadrup, nge Marie Svane

Refined analytical pipeline for the pharmacodynamic assessment of T-cell responses to vaccine antigens

Apr 24, 2024

Publications

Refined analytical pipeline for the pharmacodynamic assessment of T-cell responses to vaccine antigens

Publication: Frontiers in Immunology
Authors: Michail Angelos Pavlidis, Nadia Viborg, Mads Lausen, Birgitte Rønø and Daniela Kleine-Kohlbrecher

Startups probe hidden viruses in the ‘dark genome’ to treat disease

Apr 17, 2024

Publications

Startups probe hidden viruses in the ‘dark genome’ to treat disease

Publication: Nature Biotechnology
Author: Michael Eisenstein

Personalized Neoantigen DNA Cancer Vaccines: Current Status and Future Perspectives

Mar 14, 2024

Publications

Personalized Neoantigen DNA Cancer Vaccines: Current Status and Future Perspectives

Publication: Journal of Cellular Immunology
Author: Nadia Viborg, Daniela Kleine-Kohlbrecher and Birgitte Rønø

Preclinical efficacy of a cell division protein candidate gonococcal vaccine identified by artificial intelligence

Oct 31, 2023

Publications

Preclinical efficacy of a cell division protein candidate gonococcal vaccine identified by artificial intelligence

Publication: mBio
Authors: Sunita Gulati, Andreas Holm Mattsson, Sophie Schussek, Bo Zheng, Rosane B. DeOliveira, Jutamas Shaughnessy, Lisa A. Lewis, Peter A. Rice, Pär Comstedt, Sanjay Ram

Targeting neoantigens to APC- surface molecules improves the immunogenicity and anti-tumor efficacy of a DNA cancer vaccine

Aug 29, 2023

Publications

Targeting neoantigens to APC- surface molecules improves the immunogenicity and anti-tumor efficacy of a DNA cancer vaccine

Publication: Frontier in Immunology 
Authors: Marina Barrio-Calvo, Søren Vester Kofoed, Sofie Cens Holste, Anders Bundgård Sørensen, Nadia Viborg, Jens Vindahl Kringelum, Daniela Kleine-Kohlbrecher, Christian Skjødt Steenmans, Christian Bahne Thygesen, Birgitte Rønø and Stine Friis